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AI drug discovery startups

Protein design, molecular structure and AI-first drug discovery. We track 6 labs in this area, which have raised $1.79B in disclosed rounds between them; the most valuable is Chai Discovery, at $3.8B.

6labs
$1.79Bdisclosed raised
$0Mreported valuations
LabTopicLocationFounders fromFoundedLast roundValuationRaisedStatus
Chai DiscoveryMolecular structure prediction and antibody design (Chai-1, Chai-2), used by Pfizer, Lilly…site Biology & drug discovery San Francisco, US ex-OpenAI, ex-Stripe, ex-Aqemia, ex-UChicago 2024 · $3.8Best. · API
Merge LabsBrain-computer interfaces co-founded by Sam Altman; backed by OpenAI.site Biology & drug discovery San Francisco, US ex-OpenAI, ex-Tools for Humanity, ex-Caltech 2025 · $850Mest. · Research only
EvolutionaryScaleESM3 protein language models; the team later joined Biohub.site Biology & drug discovery New York, US ex-Meta 2023 Seed $142MJun 25, 2024 · Nat Friedman, Daniel Gross, Lux Capital · $142M Merged
Isomorphic LabsDrug discovery beyond AlphaFold; an Alphabet subsidiary with pharma partnerships.site · in Biology & drug discovery London, UK ex-Google DeepMind 2021 Series A $600MMar 31, 2025 · Thrive Capital · $600M Partnerships
Latent LabsProtein and antibody design with a wet lab, from an AlphaFold co-developer.site Biology & drug discovery London, UK ex-Google DeepMind 2023 Series A $50MFeb 11, 2025 · Radical Ventures, Sofinnova Partners · $50M API
Xaira TherapeuticsAI-first drug discovery launched with $1B.site · in Biology & drug discovery South San Francisco, US ex-Stanford, ex-UW, ex-Google DeepMind, ex-Meta 2024 Series A $1BApr 23, 2024 · ARCH Venture Partners, Foresite Capital · $1B Research only

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